Wine Spectator Award of Excellence 2026 · Happy Hour Tue-Fri 4-6 · Reserve Now →

A modern American wine & cocktail bar with Spanish influence, on East Jefferson in Detroit.

A Cure for the Ordinary

Dinner should feel like something.

Modern American plates with Spanish influence. A wine list recognized by Wine Spectator, cocktails built for evenings that linger, and a room of velvet teal and golden light made for date night in Detroit. Brunch on weekends, happy hour Tuesday through Friday, and a patio in season, minutes from the Schaap Center for the Performing Arts and Belle Isle.

14628 E Jefferson Ave · Detroit · Free parking on site
Every hour has its antidote

On the table this week

Rioja-braised short rib hash with a sunny egg on a salmon plate

Brunch

Sat 11-3 · Sun 11-4See menu
Spiced ribeye with chimichurri and grilled asparagus

Dinner

Tue-Thu 4-10 · Fri-Sat 4-12Happy Hour · Tue-Fri 4-6See menu
A stirred cocktail with a cherry at the Antidote bar

The Bar

Wine by the glass · Cocktails · Late night Fri-SatWine & cocktails
2026Wine Spectator
Award of Excellence

Wine, curated.

From Penedès cava and Getariako Txakolina to Priorat, Rioja, and old-vine finds across two continents. A list built to move with the menu and evolve with the evening. Corkage $25. Reserve offerings on request.

Cocktail service at Antidote's bar
New

The Antidote Wine Club

The ANTIDÓTE Wine Club is coming soon. Join the interest list to receive launch details when membership information is finalized.

01

Coming Soon

Membership details will be announced after the program is finalized.

02

Stay Informed

Join the interest list for future Wine Club announcements.

03

Final Details

Pricing, benefits, and launch timing will be shared when confirmed.

Founding memberships open soon. Join the list for first invitations.

Antidote's patio at dusk with string lights, fire tables, and lounge seating
Now open

The Patio

Patio seating may be available seasonally, weather permitting. Please contact the restaurant for current availability.

On the calendar

Events at Antidote

Monthly

Wine Dinner Series

Follow Antidóte for verified event announcements, wine experiences, and seasonal gatherings.

Sundays

Brunch on Jefferson

Lemon ricotta pancakes, Rioja-braised short rib hash, and pitchers of sangria. 11 to 4.

Tue-Fri

Happy Hour

Join us Tuesday through Friday from 4 to 6 PM for Antidóte Happy Hour. Ask the restaurant for the current approved offerings.

Showtimes

Pre-Theater Dinner

Heading to the Schaap Center? Tell us your curtain time and we will pace the evening.

Follow along for upcoming wine dinners, tastings, and seasonal gatherings.

Antidote's dining room with arched wall niches and teal banquettes
Private events

Celebrate with intention.

Birthdays, anniversaries, corporate and client dinners, celebrations, social gatherings, group dining, and full restaurant buyouts when available. Our team works with you to shape the experience without publishing unconfirmed capacities or package details.

Featured in
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Follow along

Good to know

We’re at 14628 E Jefferson Ave in Detroit’s Jefferson-Chalmers neighborhood, near the Grosse Pointe Park border, with a free parking lot attached to the building.

Yes. Our patio has fire tables, string lights, and full food and drink service, seasonally and weather permitting.

Reservations are recommended, especially Friday and Saturday evenings. Book through SevenRooms, or walk in and join us at the bar.

Tuesday through Friday, 4 to 6 pm: $10 classic cocktails (Old Fashioned, Manhattan, Daiquiri, Sidecar, Lemon Drop, Negroni), 25% off wine and zero-proof cocktails, $3 lager, $6 beer and a shot, and a $10 bites menu including albondigas, patatas bravas, truffle-potato pavé, and sautéed shrimp. Ask about our break-even pour.

We’re minutes away. Ideal for pre-theater dinner or post-show cocktails and dessert. Tell us your curtain time and we’ll pace the meal.

Members pick up two curated bottles each month at the bar, get first seats at wine dinners, and corkage is waived on club bottles when you dine with us. Join the founding list above.

Yes. We host birthdays, showers, corporate dinners, and pharmaceutical and medical education dinners, from intimate gatherings to full buyouts of our 76-seat room. Share your date, guest count, and occasion through the private events form and our team will follow up.

It was designed for it. Velvet teal booths, golden light, a Wine Spectator-recognized wine list, and a menu made for sharing. One of the east side’s best date night spots, minutes from Belle Isle.

Modern American with Spanish influence: albóndigas, patatas bravas, truffle-potato pavé, piri-piri roasted chicken, and Basque cheesecake, alongside a Wine Spectator-recognized wine list and signature cocktails.

Yes. The menu marks vegetarian and gluten-free dishes, and our kitchen is happy to guide you through options. Tell your server about any allergies and we will take care of you.

You are welcome to bring a special bottle. Corkage is $25, and it is waived on Wine Club bottles when you dine with us.

Dress to enjoy yourself. Most guests land somewhere between smart casual and dressed up for date night. Come as you are comfortable.

Yes. Our room seats 76, and we host large groups regularly. For parties of eight or more, or anything you want to make special, reach out through the private events form and we will set it up.

Yes. Our dining room, patio, and restrooms are wheelchair accessible, with accessible parking in our free lot. If you have specific needs, call us at (313) 499-8129 and we will make sure your visit is easy.

Yes. Antidote gift cards are available at the restaurant, perfect for date nights, birthdays, and holidays. Ask your server or call us to arrange one.

Antidote is a dine-in experience by design. We do not offer delivery, though we are happy to package dessert or a remaining bottle per Michigan law. For the full experience, reserve a table.

Families are welcome, especially at weekend brunch. Evenings lean toward date night and grown-up celebrations, so little ones may enjoy brunch hours most.

Evenings worth lingering over.